Quick answer: ARA-290 and cibinetide are two names for the same short peptide. It is also written as ARA290 or pHBSP (pyroglutamyl helix B surface peptide). It is not erythropoietin (EPO), and it is not the same as other helix B peptides, so the name on the label and the Certificate of Analysis matter.
What other names does ARA-290 go by?
Listings use several labels for this compound. Most are spelling variants or older research names. A few refer to different molecules, which is where mix-ups start.
| Name | What it refers to | Same as ARA-290? |
|---|---|---|
| ARA-290, Ara-290, ARA290, ARA 290 | Spelling variants of one catalog name | Yes |
| Cibinetide | The generic name used for the same peptide | Yes |
| pHBSP | Pyroglutamyl helix B surface peptide, the descriptive research name | Yes |
| EPO or erythropoietin | The full-length protein that ARA-290 is derived from | No |
| CHBP | Cyclic helix B peptide, a separate, related peptide | No |
How is ARA-290 different from erythropoietin?
Erythropoietin is a large protein. ARA-290 is a short chain of 11 amino acids built from the helix B region of that protein, with a pyroglutamate group at one end. The name pHBSP describes exactly that.
The size difference changes the target. Researchers describe ARA-290 as interacting with the innate repair receptor (IRR), which is proposed to be a partnership of the EPO receptor and a second receptor subunit called the beta common receptor. Our product page describes ARA-290 as designed to avoid erythropoietic activity, meaning the activity tied to red blood cell production. That is the reason it gets its own name and its own research interest.
Is cyclic helix B peptide (CHBP) the same thing?
No. CHBP is also taken from the helix B region of EPO, but it is a different molecule with a different structure. It is a cyclic peptide, so its chain is closed into a ring. ARA-290 is not.
Published work on the two is not interchangeable. If a listing or a paper says “helix B peptide” without more detail, check which one it means before comparing results.
Do salt forms and versions change what is in the vial?
The peptide sequence stays the same, but the powder can differ. Synthetic peptides are often supplied as a salt, with a leftover counterion from purification such as acetate or trifluoroacetate (TFA). The counterion adds weight, so the milligram figure on a label is not always pure peptide.
This is why a COA matters beyond the name. A clear COA states the identity, the purity and what the vial content refers to. For the general reasoning, see our line-by-line guide to reading a Certificate of Analysis.
What is in our ARA-290 20mg vial?
Our ARA-290 | 20mg product is a single-compound research peptide. It is the helix B-derived peptide described above, not a blend and not a different helix B fragment. The product page describes it as research-grade, made in the USA, third-party tested and supported by verified COAs. Our peptides are synthesized at a WHO/GMP and ISO 9001 certified laboratory in California.
The product page lists a vial size of 20mg and does not list a CAS number, formula or molecular weight, so we do not quote them here. Like most research peptides it is a dry powder, a format covered in our lyophilization explainer.
How do you confirm a vial really is ARA-290?
A name on a label proves nothing by itself. Three checks on the COA tell you more:
- Identity by mass: the measured mass should match the expected mass for the 11-residue sequence. A different helix B peptide would show a different mass.
- Purity by HPLC: this shows how much of the sample is the main peak. It does not confirm identity on its own.
- Content per vial: look for a stated amount and what it refers to.
Also check that the compound name on the COA matches the vial and the product page, and that the batch details line up.
The COA for this product is shown above. Read it against the checks in this section.
Frequently asked questions
What does pHBSP stand for?
It stands for pyroglutamyl helix B surface peptide. It describes the pyroglutamate end group and the helix B region the sequence comes from.
How many amino acids are in ARA-290?
It has 11 amino acids, which makes it a small peptide compared with the full EPO protein.
Is ARA-290 a protein or a peptide?
It is a peptide. It is a short synthetic chain modeled on one region of a much larger protein.
Why do some listings write ARA290 without a hyphen?
It is only a spelling habit. The hyphen, no hyphen and the spaced version all point to the same catalog name.
Which receptor is ARA-290 studied against?
Published laboratory research, mostly cell and preclinical work, examines it at the innate repair receptor. The evidence is still early, and the receptor’s exact makeup is still discussed.
Does the salt form change the peptide sequence?
No. It changes what else is in the powder and how much the vial weighs for the same amount of peptide, which is why the COA should state what its content figure refers to.
Every lot we sell has a Certificate of Analysis you can read before you order. Questions before you buy? Our team is in Chandler, Arizona: (888) 745-1505 or our contact page.
View ARA-290 | 20mgAll products sold by BioPure Peptides are intended strictly for in-vitro laboratory and research use only. They are not for human or animal consumption. These statements have not been evaluated by the U.S. Food and Drug Administration, and these products are not intended to diagnose, treat, cure, or prevent any disease.